CGMS
Continuous Glucose Monitoring System
Necessity of CGMS
Global Diabetes Increase: Owing to shifts in dietary patterns and the aging
global population, the worldwide diabetic population has been steadily
growing, reaching 530 million by 2021.
Notably, 11.3% of global deaths are attributed to diabetes-related complications.
Furthermore, the demand for close self-management of blood sugar levels continues to rise.
Type 1 Diabetes Challenges: Individuals with Type 1 diabetes face a greater risk of hypoglycemic shocks and complications compared to those with Type 2 diabetes. Therefore, it is imperative to enhance their quality of life and prevent diabetes-related complications by ensuring effective and secure insulin administration through Continuous Glucose Monitoring Systems (CGMS).
Blood Sugar Monitoring: Blood sugar levels are monitored using an enzyme-based sensor that initiates an electrochemical reaction after each needle prick. However, relying solely on single-point blood sugar readings obtained from finger pricks 4-5 times a day has limitations in meeting the continuous blood sugar monitoring needs of Type-1 diabetic patients, who suffer from insufficient insulin secretion due to pancreatic beta cell abnormalities.
Furthermore, the demand for close self-management of blood sugar levels continues to rise.
Type 1 Diabetes Challenges: Individuals with Type 1 diabetes face a greater risk of hypoglycemic shocks and complications compared to those with Type 2 diabetes. Therefore, it is imperative to enhance their quality of life and prevent diabetes-related complications by ensuring effective and secure insulin administration through Continuous Glucose Monitoring Systems (CGMS).
Blood Sugar Monitoring: Blood sugar levels are monitored using an enzyme-based sensor that initiates an electrochemical reaction after each needle prick. However, relying solely on single-point blood sugar readings obtained from finger pricks 4-5 times a day has limitations in meeting the continuous blood sugar monitoring needs of Type-1 diabetic patients, who suffer from insufficient insulin secretion due to pancreatic beta cell abnormalities.
The currently available continuous blood glucose monitoring system doesn't require blood withdrawal on every occasion.
Instead, it utilizes an enzyme-based needle sensor inserted about 5mm beneath the skin's surface in the interstitial layer.
This sensor continuously records blood glucose levels at five-minute intervals over a two-week period. However, the
replacement of this sensor, which is valued at about $80, can be costly for patients. Additionally, the use of adhesive
tape to secure the sensor can lead to skin issues. Furthermore, there is a time delay associated with readings from the
interstitial layer, which does not involve blood collection on each occasion. This system also carries the risk of
hypoglycemic shock in the event of sudden blood glucose fluctuations.
Instead, it utilizes an enzyme-based needle sensor inserted about 5mm beneath the skin's surface in the interstitial layer.
This sensor continuously records blood glucose levels at five-minute intervals over a two-week period. However, the
replacement of this sensor, which is valued at about $80, can be costly for patients. Additionally, the use of adhesive
tape to secure the sensor can lead to skin issues. Furthermore, there is a time delay associated with readings from the
interstitial layer, which does not involve blood collection on each occasion. This system also carries the risk of
hypoglycemic shock in the event of sudden blood glucose fluctuations.
Micro-sensor technology using electromagnetic waves
and low-power system semiconductors
Micro-sensor technology using electromagnetic waves and low-power system semiconductors
